I just got Skin Trade by Laurell K Hamilton yesterday. I started reading it at 11 a.m., and had finished it by midnight (this was in between physical therapy appointment, fixing and eating lunch, fixing dinner, keeping up with email and Google reader, etc). I think I spent a total of 6 hours reading 486 pages.
It was time well-spent, IMNSHO. There was way less sex in this book of the Anita Blake series, and a lot more about Anita's developing powers and her psychological problems with what she does, on the job and in her personal life. Don't get me wrong, the sex scenes in the books are good, but getting more into what is going on in Anita's mind and going deeper into her interactions with the vampires and weres that she deals with (not to mention her interactions with Edward and Olaf) makes for a much more interesting read.
I like all of the books in this series, but I think that this one is my favorite, to date (it's the first one I've read, cover-to-cover, the first day I got it).